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CANCER GENES

A number of cancer genes are more common in Jews than in the general population

BRCA1

Women carrying a BRCA 1 mutation have a 72% likelihood of developing breast cancer by age 80, which is more than five times the risk of the general population.

BRCA2

Women with a BRCA 2 mutation have a 69% likelihood of developing and a 44% likelihood of developing ovarian cancer, which is over thirty times the risk of the general population.

APC I1307K allele

Associated with increased risk of colorectal cancer.